iPTMnet Report for Q9H3S1 (SEMA4A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H3S1 / SEM4A_HUMAN
Protein Name Semaphorin-4A precursor
Gene Name Name: SEMA4A
Synonyms:SEMAB,SEMB;ORFNames:UNQ783/PRO1317;
Organism Homo sapiens (Human)

PRO ID PR:Q9H3S1
DAG View
PRO Name semaphorin-4A (human)
Definition A semaphorin-4A that is encoded in the genome of human.
Short Label hSEMA4A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H3S1 (SEMA4A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y44 Phosphorylation PhosphoSitePlus
Y45 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
N120 N-Glycosylation GlyGen 24190977
K219 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
T440 Phosphorylation PhosphoSitePlus
N496 N-Glycosylation GlyGen 24190977
K535 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
T721 Phosphorylation PhosphoSitePlus
K727 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T522 Phosphorylation HPRD 18452278
S533 Phosphorylation HPRD 18452278
S549 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K59 E59 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K277 N277 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K662 N662 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K715 N715 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T721 I721 Biomuta DOID:4159 / skin cancer [ cosmic ]
K727 N727 Biomuta DOID:9256 / colorectal cancer [ cosmic ]