iPTMnet Report for Q9H3R5 (CENPH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H3R5 / CENPH_HUMAN
Protein Name Centromere protein H
Gene Name Name: CENPH
Synonyms:ICEN35;
Organism Homo sapiens (Human)

PRO ID PR:Q9H3R5
DAG View
PRO Name centromere protein H (human)
Definition A centromere protein H that is encoded in the genome of human.
Short Label hCENPH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H3R5 (CENPH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
S16 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19691289
R21 Methylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
T68 Phosphorylation PhosphoSitePlus   UniProt 23186163
K76 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R21 L21 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S124 I124 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K138 N138 Biomuta DOID:263 / kidney cancer [ cosmic ]
K171 Q171 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K183 R183 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]