iPTMnet Report for Q9H3R0 (KDM4C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H3R0 / KDM4C_HUMAN
Protein Name Lysine-specific demethylase 4C
Gene Name Name: KDM4C
Synonyms:GASC1,JHDM3C,JMJD2C,KIAA0780;
Organism Homo sapiens (Human)

PRO ID PR:Q9H3R0
DAG View
PRO Name lysine-specific demethylase 4C (human)
Definition A lysine-specific demethylase 4C that is encoded in the genome of human.
Short Label hKDM4C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H3R0 (KDM4C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
T245 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
K671 Ubiquitination PhosphoSitePlus
K772 Acetylation PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
T903 Phosphorylation PhosphoSitePlus
T906 Phosphorylation PhosphoSitePlus
Y908 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
K933 Ubiquitination PhosphoSitePlus
K946 Ubiquitination PhosphoSitePlus
K951 Ubiquitination PhosphoSitePlus
T985 Phosphorylation PhosphoSitePlus
K992 Ubiquitination PhosphoSitePlus
T1009 Phosphorylation PhosphoSitePlus
K1031 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S248 Y248 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S248 C248 Biomuta DOID:3571 / liver cancer [ cosmic ]
S250 L250 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K254 E254 Biomuta DOID:1612 / breast cancer [ cosmic ]
K306 T306 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K338 N338 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S576 N576 Biomuta DOID:1324 / lung cancer [ cosmic ]
K772 R772 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ icgc ]
Y908 S908 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S918 I918 Biomuta DOID:1324 / lung cancer [ cosmic ]