iPTMnet Report for Q9H3Q1 (CDC42EP4)
Protein Information
UniProt AC / UniProt ID | Q9H3Q1 / BORG4_HUMAN |
Protein Name | Cdc42 effector protein 4 |
Gene Name | Name: CDC42EP4 Synonyms:BORG4,CEP4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H3Q1 |
PRO Name | Cdc42 effector protein 4 (human) |
Definition | A Cdc42 effector protein 4 that is encoded in the genome of human. |
Short Label | hCDC42EP4 |
Category | organism-gene |
Q9H3Q1 (CDC42EP4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K5 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | P17252 (PRKCA) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P+ Signor | 18669648, 25086031 | |
T23 | Phosphorylation | score1 | PhosphoSitePlus | |||
R42 | Methylation | score1 | PhosphoSitePlus | |||
T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S51 | Phosphorylation | score1 | PhosphoSitePlus | |||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231, ... | ||
S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
K75 | Ubiquitination | score1 | PhosphoSitePlus | |||
S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
S80 | Phosphorylation | P17252 (PRKCA) | score3 | PhosphoSitePlus RLIMS-P+ Signor | 25086031 | |
S86 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
S89 | Phosphorylation | score1 | PhosphoSitePlus | |||
S91 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S109 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
S118 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
S138 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 17081983 | ||
S140 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 17081983, 20068231 | ||
S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
S142 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 17081983, ... | ||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
S174 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 20068231, 18669648, 17081983, ... | ||
T188 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
Y255 | Phosphorylation | score1 | PhosphoSitePlus | |||
S292 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 17081983, 18220336 | ||
S295 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 17081983, 20068231, ... | ||
S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
S344 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S14 | Phosphorylation | score0 | HPRD | 20068231 | ||
S18 | Phosphorylation | score0 | HPRD | 18669648 | ||
S64 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 19664994, ... | ||
S118 | Phosphorylation | score0 | HPRD | 19664994, 20068231 | ||
S138 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
S140 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
S141 | Phosphorylation | score0 | HPRD | 19651622 | ||
S142 | Phosphorylation | score0 | HPRD | 16964243, 17081983, 19651622, ... | ||
S174 | Phosphorylation | score0 | HPRD | 18212344, 18452278, 19651622, ... | ||
T188 | Phosphorylation | score0 | HPRD | 18669648 | ||
S292 | Phosphorylation | score0 | HPRD | 19651622, 18691976, 18669648, ... | ||
S295 | Phosphorylation | score0 | HPRD | 19651622, 18691976, 18669648, ... | ||
S298 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S11 | L11 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] | |
R42 | L42 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S77 | G77 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S91 | L91 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S91 | P91 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S105 | F105 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S109 | L109 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] | |
K125 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y255 | C255 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S292 | I292 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S295 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S344 | F344 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |