iPTMnet Report for Q9H3P2 (NELFA)
Protein Information
UniProt AC / UniProt ID | Q9H3P2 / NELFA_HUMAN |
Protein Name | Negative elongation factor A |
Gene Name | Name: NELFA Synonyms:WHSC2;ORFNames:P/OKcl.15; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H3P2 |
PRO Name | negative elongation factor A (human) |
Definition | A negative elongation factor A that is encoded in the genome of human. |
Short Label | hNELFA |
Category | organism-gene |
Q9H3P2 (NELFA) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S7 | Phosphorylation | score1 | PhosphoSitePlus | |||
C44 | Methylation | score1 | IEDB | 31844290 | ||
T60 | Phosphorylation | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
C131 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
C141 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
T157 | Phosphorylation | P24941 (CDK2) | score2 | PhosphoSitePlus UniProt | 23186163, 16964243, 18847512, ... | |
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
K190 | Methylation | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
K200 | Methylation | score1 | PhosphoSitePlus | |||
R202 | Methylation | score1 | PhosphoSitePlus | |||
T212 | Phosphorylation | score1 | PhosphoSitePlus | |||
S225 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T227 | Phosphorylation | score1 | PhosphoSitePlus | |||
S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
S233 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T235 | Phosphorylation | score1 | PhosphoSitePlus | |||
R238 | Methylation | score1 | PhosphoSitePlus | |||
T239 | Phosphorylation | score1 | PhosphoSitePlus | |||
T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
K255 | Acetylation | score1 | PhosphoSitePlus | |||
S260 | Phosphorylation | score1 | PhosphoSitePlus | |||
T277 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
K285 | Acetylation | score1 | PhosphoSitePlus | |||
K288 | Sumoylation | score1 | PhosphoSitePlus | |||
T291 | Phosphorylation | score1 | PhosphoSitePlus | |||
T297 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y300 | Phosphorylation | score1 | PhosphoSitePlus | |||
T328 | Phosphorylation | score1 | PhosphoSitePlus | |||
S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
S336 | Phosphorylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
T343 | Phosphorylation | score1 | PhosphoSitePlus | |||
S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S349 | Phosphorylation | score1 | PhosphoSitePlus | |||
S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
S360 | Phosphorylation | score1 | PhosphoSitePlus | |||
S363 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 20068231, ... | ||
T365 | Phosphorylation | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
K429 | Ubiquitination | score1 | PhosphoSitePlus | |||
K446 | Methylation | score1 | PhosphoSitePlus | |||
K446 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y521 | Phosphorylation | score1 | PhosphoSitePlus | |||
S528 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R202 | L202 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
R202 | W202 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R202 | Q202 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |