iPTMnet Report for Q9H3H1 (TRIT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H3H1 / MOD5_HUMAN
Protein Name tRNA dimethylallyltransferase precursor
Gene Name Name: TRIT1
Synonyms:IPT,MOD5;
Organism Homo sapiens (Human)

PRO ID PR:Q9H3H1
DAG View
PRO Name tRNA dimethylallyltransferase (human)
Definition A eukaryotic tRNA dimethylallyltransferase that is encoded in the genome of human.
Short Label hTRIT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H3H1 (TRIT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K315 Acetylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
T436 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus   UniProt 23186163
S455 Phosphorylation PhosphoSitePlus   UniProt 20068231
Site PTM Type PTM Enzyme Score Source PMID
T103 Phosphorylation HPRD 17693683
S167 Phosphorylation HPRD 18077418
S431 Phosphorylation HPRD 18077418
T436 Phosphorylation HPRD 18077418
S439 Phosphorylation HPRD 18077418
S443 Phosphorylation HPRD 19651622, 18077418, 17081983, ...20068231
S455 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 I14 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T103 I103 Biomuta DOID:4159 / skin cancer [ cosmic ]
K138 T138 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T436 N436 Biomuta DOID:3571 / liver cancer [ cosmic ]
S455 P455 Biomuta DOID:363 / uterine cancer [ icgc ]