iPTMnet Report for Q9H3F6 (KCTD10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H3F6 / BACD3_HUMAN
Protein Name BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3
Gene Name Name: KCTD10
Synonyms:ULR061;ORFNames:MSTP028;
Organism Homo sapiens (Human)

PRO ID PR:Q9H3F6
DAG View
PRO Name BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (human)
Definition A BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 that is encoded in the genome of human.
Short Label hKCTD10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H3F6 (KCTD10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S5 Phosphorylation PhosphoSitePlus
S23 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K25 Ubiquitination PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation HPRD 18669648, 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 T23 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T27 A27 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K171 T171 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K184 I184 Biomuta DOID:1324 / lung cancer [ cosmic ]