iPTMnet Report for Q9H361 (PABPC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H361 / PABP3_HUMAN
Protein Name Polyadenylate-binding protein 3
Gene Name Name: PABPC3
Synonyms:PABP3,PABPL3;
Organism Homo sapiens (Human)

PRO ID PR:Q9H361
DAG View
PRO Name polyadenylate-binding protein 3 (human)
Definition A polyadenylate-binding protein 3 that is encoded in the genome of human.
Short Label hPABPC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H361 (PABPC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation PhosphoSitePlus
Y56 Phosphorylation PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K188 Methylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K213 Acetylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
R240 Methylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K259 Acetylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
R309 Methylation PhosphoSitePlus
S315 O-Glycosylation GlyGen 34105348
S315 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
R426 Methylation PhosphoSitePlus
R430 Methylation PhosphoSitePlus
R437 Methylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
R461 Methylation PhosphoSitePlus
R469 Methylation PhosphoSitePlus
R475 Methylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
Y508 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
T630 O-Glycosylation GlyGen 34019948, 30620550, 34105348, ...35254053
T630 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K78 E78 Biomuta DOID:4159 / skin cancer [ cosmic ]
K80 E80 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K108 M108 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K188 N188 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K208 N208 Biomuta DOID:1324 / lung cancer [ cosmic ]
K213 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K213 N213 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
S219 G219 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K231 E231 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K284 Q284 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R309 H309 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
Y364 F364 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R426 K426 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R430 H430 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
R437 K437 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S458 N458 Biomuta DOID:4159 / skin cancer [ cosmic ]
S458 R458 Biomuta DOID:2394 / ovarian cancer [ icgc ]
R469 * Biomuta DOID:1612 / breast cancer [ cosmic ]
R469 Q469 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
R469 G469 Biomuta DOID:1324 / lung cancer [ cosmic ]
R475 H475 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R475 C475 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]