iPTMnet Report for Q9H2X9 (SLC12A5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H2X9 / S12A5_HUMAN
Protein Name Solute carrier family 12 member 5
Gene Name Name: SLC12A5
Synonyms:KCC2;
Organism Homo sapiens (Human)

PRO ID PR:Q9H2X9
DAG View
PRO Name solute carrier family 12 member 5 (human)
Definition A solute carrier family 12 member 5 that is encoded in the genome of human.
Short Label hSLC12A5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H2X9 (SLC12A5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T6 Phosphorylation Q9UEW8 (STK39) PhosphoSitePlus 24393035
S27 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
T501 Phosphorylation PhosphoSitePlus
Y617 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
T821 Phosphorylation PhosphoSitePlus
T831 Phosphorylation PhosphoSitePlus
T929 Phosphorylation PhosphoSitePlus   UniProt 19665974
S963 Phosphorylation PhosphoSitePlus
T1030 Phosphorylation PhosphoSitePlus   UniProt 19665974
T1032 Phosphorylation Q9UEW8 (STK39) PhosphoSitePlus 24393035
Y1110 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 N2 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S27 T27 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S54 N54 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S622 C622 Biomuta DOID:1324 / lung cancer [ cosmic ]
S622 F622 Biomuta DOID:4159 / skin cancer [ cosmic ]
S622 Y622 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T929 M929 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]