Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H2P9 / DPH5_HUMAN
Protein Name Diphthine methyl ester synthase
Gene Name Name: DPH5
ORFNames:AD-018,CGI-30,HSPC143,NPD015;
Organism Homo sapiens (Human)

PRO ID PR:Q9H2P9
DAG View
PRO Name diphthine methyl ester synthase (human)
Definition A diphthine methyl ester synthase that is encoded in the genome of human.
Short Label hDPH5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H2P9 (DPH5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y3 Phosphorylation PhosphoSitePlus
T16 Phosphorylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus   UniProt 23186163
K177 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
Y187 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y30 Phosphorylation HPRD 20068231
T35 Phosphorylation HPRD 20068231
S36 Phosphorylation HPRD 20068231
T236 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y30 Phosphorylation HPRD 20068231
T35 Phosphorylation HPRD 20068231
S36 Phosphorylation HPRD 20068231
T235 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K18 R18 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S36 * Biomuta DOID:4362 / cervical cancer [ tcga ]
S171 Y171 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K177 E177 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K180 N180 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]