iPTMnet Report for Q9H2H9 (SLC38A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H2H9 / S38A1_HUMAN
Protein Name Sodium-coupled neutral amino acid symporter 1
Gene Name Name: SLC38A1
Synonyms:ATA1;
Organism Homo sapiens (Human)

PRO ID PR:Q9H2H9
DAG View
PRO Name sodium-coupled neutral amino acid symporter 1 (human)
Definition A sodium-coupled neutral amino acid symporter 1 that is encoded in the genome of human.
Short Label hSLC38A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H2H9 (SLC38A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 18669648
S28 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 18669648
T32 Phosphorylation HPRD   PhosphoSitePlus 18669648
S41 Phosphorylation HPRD   PhosphoSitePlus 18691976
S45 Phosphorylation PhosphoSitePlus
S49 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19691289, 20068231, ...18452278
S52 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...18767875, 18578522, 19664995, 19651622, 18669648, 18707149, 20068231, 19691289
T54 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 21406692, 18767875, ...19691289, 18452278, 19651622, 18669648, 20068231
S56 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18767875, 19651622, ...18669648, 20068231
K60 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
T265 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S45 F45 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K60 T60 Biomuta DOID:363 / uterine cancer [ icgc ]
K136 N136 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T265 K265 Biomuta DOID:184 / bone cancer [ cosmic ]
T265 M265 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K384 N384 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]