Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H2G4 / TSYL2_HUMAN
Protein Name Testis-specific Y-encoded-like protein 2
Gene Name Name: TSPYL2
Synonyms:CDA1,DENTT,TSPX;ORFNames:HRIHFB2216;
Organism Homo sapiens (Human)

PRO ID PR:Q9H2G4
DAG View
PRO Name testis-specific Y-encoded-like protein 2 (human)
Definition A testis-specific Y-encoded-like protein 2 that is encoded in the genome of human.
Short Label hTSPYL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H2G4 (TSPYL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Ubiquitination PhosphoSitePlus
S16 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 17081983, ...20068231
S17 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 17081983, ...20068231
S18 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S20 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 11395479, 20068231
S182 Phosphorylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PhosphoSitePlus
Y311 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
T340 Phosphorylation P24941 (CDK2) HPRD   PhosphoSitePlus   UniProt 11395479
K384 Ubiquitination PhosphoSitePlus
K407 Methylation PhosphoSitePlus
K414 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T340 N340 Biomuta DOID:1324 / lung cancer [ cosmic ]
K384 R384 Biomuta DOID:363 / uterine cancer [ tcga ]