iPTMnet Report for Q9H2G2 (SLK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H2G2 / SLK_HUMAN
Protein Name STE20-like serine/threonine-protein kinase
Gene Name Name: SLK
Synonyms:KIAA0204,STK2;
Organism Homo sapiens (Human)

PRO ID PR:Q9H2G2
DAG View
PRO Name STE20-like serine/threonine-protein kinase (human)
Definition A STE20-like serine/threonine-protein kinase that is encoded in the genome of human.
Short Label hSLK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H2G2 (SLK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
Y21 Phosphorylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
T183 Phosphorylation PhosphoSitePlus
S189 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19369195, ...18669648, 29493099, 20068231
T193 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y195 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T206 Phosphorylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus   UniProt 18691976
S336 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus   UniProt 23186163
S344 Phosphorylation PhosphoSitePlus   UniProt 19369195
S347 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   Signor   UniProt 17525332, 21406692, 18669648, ...16837460
S348 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   Signor   UniProt 17525332, 21406692, 18669648, ...16837460
S354 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
C358 S-Nitrosylation dbSNO 26338901
S362 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus   UniProt 24275569
K384 Ubiquitination PhosphoSitePlus
R415 Methylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
T494 Phosphorylation PhosphoSitePlus
T506 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K524 Ubiquitination PhosphoSitePlus
T545 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
T551 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...19369195, 24275569
T569 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S571 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 24275569, 20068231
K583 Ubiquitination PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
S646 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus   UniProt 18691976
K663 Ubiquitination PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
S689 Phosphorylation IEDB 35494241
S728 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
T755 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S772 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T774 Phosphorylation PhosphoSitePlus
K775 Methylation PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
S777 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S779 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S781 Phosphorylation PhosphoSitePlus
T785 Phosphorylation PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus   UniProt 23186163
S816 Phosphorylation PhosphoSitePlus
S818 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T820 Phosphorylation PhosphoSitePlus
K839 Ubiquitination PhosphoSitePlus
S850 Phosphorylation PhosphoSitePlus
K851 Ubiquitination PhosphoSitePlus
K917 Ubiquitination PhosphoSitePlus
K1024 Ubiquitination PhosphoSitePlus
Y1052 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation PhosphoSitePlus
S1094 Phosphorylation PhosphoSitePlus
T1097 Phosphorylation PhosphoSitePlus   UniProt 20068231
K1106 Ubiquitination PhosphoSitePlus
K1114 Ubiquitination PhosphoSitePlus
C1153 S-Nitrosylation dbSNO 26338901
K1187 Ubiquitination PhosphoSitePlus
T1188 Phosphorylation PhosphoSitePlus
K1196 Ubiquitination PhosphoSitePlus
K1205 Methylation PhosphoSitePlus
C1212 S-Nitrosylation dbSNO 26338901
S1219 Phosphorylation PhosphoSitePlus
Y1225 Phosphorylation PhosphoSitePlus
S1229 Phosphorylation PhosphoSitePlus
S1235 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20058876
T139 Phosphorylation HPRD 20068231
T181 Phosphorylation HPRD 20068231
T183 Phosphorylation HPRD 18691976, 20068231
S189 Phosphorylation HPRD 18691976, 17081983, 20058876, ...19651622, 18669648, 20068231
T193 Phosphorylation HPRD 18691976, 18669648, 20058876
Y195 Phosphorylation HPRD 18669648, 20058876, 20068231
T327 Phosphorylation HPRD 18691976
S330 Phosphorylation HPRD 18691976
S340 Phosphorylation HPRD 17322306, 18691976, 19651622
S341 Phosphorylation HPRD 18691976, 17081983
S344 Phosphorylation HPRD 18691976, 17081983
S347 Phosphorylation HPRD 18691976, 17525332, 18767875, ...19651622, 18669648, 20068231
S348 Phosphorylation HPRD 18691976, 18767875, 19651622, ...17322306, 18669648, 20068231
S354 Phosphorylation HPRD 18691976, 17525332
S370 Phosphorylation HPRD 18691976
T523 Phosphorylation HPRD 18691976
T527 Phosphorylation HPRD 20068231
S543 Phosphorylation HPRD 18691976
S546 Phosphorylation HPRD 18691976
S565 Phosphorylation HPRD 19651622, 18691976, 18452278
T569 Phosphorylation HPRD 19651622, 18691976, 18669648
S571 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231, 18452278
S623 Phosphorylation HPRD 18691976
T636 Phosphorylation HPRD 18691976
T637 Phosphorylation HPRD 18691976
S645 Phosphorylation HPRD 18691976
S646 Phosphorylation HPRD 18691976
S647 Phosphorylation HPRD 18691976
S655 Phosphorylation HPRD 18691976
T676 Phosphorylation HPRD 20068231
S717 Phosphorylation HPRD 18691976
S750 Phosphorylation HPRD 18691976
T752 Phosphorylation HPRD 18691976
S754 Phosphorylation HPRD 18691976
T755 Phosphorylation HPRD 18691976, 17287340
S759 Phosphorylation HPRD 18691976
S772 Phosphorylation HPRD 17287340
S777 Phosphorylation HPRD 18691976, 18669648, 20068231
S779 Phosphorylation HPRD 20166139, 18691976, 18669648, ...19664994, 20068231
T785 Phosphorylation HPRD 20068231
S816 Phosphorylation HPRD 18691976
S818 Phosphorylation HPRD 18691976, 18669648
S1094 Phosphorylation HPRD 18691976
T1095 Phosphorylation HPRD 18691976
T1097 Phosphorylation HPRD 18691976, 20068231
S1229 Phosphorylation HPRD 20068231
S1232 Phosphorylation HPRD 18691976
T1233 Phosphorylation HPRD 20068231
S1235 Phosphorylation HPRD 18691976, 18669648, 20068231


Q9H2G2 (SLK) as PTM Enzyme



Substrate Site Score Source PMID
P61586 (RHOA) S188 RLIMS-P+ 18420945
Q9H2K8 (TAOK3) T181 HPRD 10559204
Q9H2K8 (TAOK3) Y183 HPRD 10559204