iPTMnet Report for Q9H254 (SPTBN4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H254 / SPTN4_HUMAN
Protein Name Spectrin beta chain, non-erythrocytic 4
Gene Name Name: SPTBN4
Synonyms:KIAA1642,SPTBN3;
Organism Homo sapiens (Human)

PRO ID PR:Q9H254
DAG View
PRO Name spectrin beta chain, non-erythrocytic 4 (human)
Definition A spectrin beta chain, non-erythrocytic 4 that is encoded in the genome of human.
Short Label hSPTBN4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H254 (SPTBN4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T41 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K131 Acetylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
T179 O-Glycosylation GlyGen 35008409, 29237092
S208 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K702 Acetylation PhosphoSitePlus
S1012 Phosphorylation PhosphoSitePlus
S1025 Phosphorylation PhosphoSitePlus
S1431 Phosphorylation PhosphoSitePlus
T1541 Phosphorylation PhosphoSitePlus
T1861 Phosphorylation PhosphoSitePlus
R1916 Methylation PhosphoSitePlus
S1939 Phosphorylation PhosphoSitePlus
S2007 Phosphorylation PhosphoSitePlus
T2111 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T2112 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S2121 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T2126 Phosphorylation PhosphoSitePlus
S2165 Phosphorylation PhosphoSitePlus
S2236 Phosphorylation PhosphoSitePlus
S2254 Phosphorylation PhosphoSitePlus
S2272 Phosphorylation PhosphoSitePlus
S2305 Phosphorylation PhosphoSitePlus
S2344 Phosphorylation PhosphoSitePlus
S2400 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T2111 Phosphorylation HPRD 20068231
T2112 Phosphorylation HPRD 20068231
S2121 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1431 I1431 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R1916 W1916 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1916 Q1916 Biomuta DOID:1324 / lung cancer [ cosmic ]
T2111 A2111 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T2112 M2112 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T2126 I2126 Biomuta DOID:2394 / ovarian cancer [ icgc ]
S2165 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S2165 L2165 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2400 C2400 Biomuta DOID:5041 / esophageal cancer [ cosmic ]