iPTMnet Report for Q9H223 (EHD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H223 / EHD4_HUMAN
Protein Name EH domain-containing protein 4
Gene Name Name: EHD4
Synonyms:HCA10;ORFNames:FKSG7;
Organism Homo sapiens (Human)

PRO ID PR:Q9H223
DAG View
PRO Name EH domain-containing protein 4 (human)
Definition An EH domain-containing protein 4 that is encoded in the genome of human.
Short Label hEHD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H223 (EHD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K35 Ubiquitination PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus   UniProt 23186163
K165 Ubiquitination PhosphoSitePlus
C175 Methylation IEDB 31844290
K208 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
Y312 Phosphorylation PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
K319 Methylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K327 Acetylation PhosphoSitePlus
K327 Methylation PhosphoSitePlus
K330 Methylation PhosphoSitePlus
K331 Acetylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
D447 Methylation IEDB 29786170
Y451 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15592455
Y456 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455
T457 Phosphorylation HPRD   PhosphoSitePlus 17081983
S459 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 19651622, ...18669648, 20068231
K478 Ubiquitination PhosphoSitePlus
S482 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S532 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S142 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K208 N208 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K223 N223 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y316 S316 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K330 R330 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S376 L376 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S406 G406 Biomuta [ cosmic ]
D447 N447 Biomuta DOID:4159 / skin cancer [ cosmic ]
S459 L459 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S536 F536 Biomuta DOID:1319 / brain cancer [ icgc ]