iPTMnet Report for Q9H1R3 (MYLK2)
Protein Information
| UniProt AC / UniProt ID | Q9H1R3 / MYLK2_HUMAN |
| Protein Name | Myosin light chain kinase 2, skeletal/cardiac muscle |
| Gene Name | Name: MYLK2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H1R3 |
| PRO Name | myosin light chain kinase 2, skeletal/cardiac muscle (human) |
| Definition | A myosin light chain kinase 2, skeletal/cardiac muscle that is encoded in the genome of human. |
| Short Label | hMYLK2 |
| Category | organism-gene |
DAG ViewQ9H1R3 (MYLK2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S151 | Phosphorylation | score2 | neXtProt | 11795875 | ||
| S151 | Phosphorylation | P49137 (MAPKAPK2) | score2 | neXtProt | 11795875 | |
| K561 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y563 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K584 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S586 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S587 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S588 | Phosphorylation | score1 | PhosphoSitePlus |
Q9H1R3 (MYLK2) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| Q06413 (MEF2C) | T80 | score3 | PhosphoSitePlus Signor | 21556048 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S588 | L588 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
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