iPTMnet Report for Q9H1I8 (ASCC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H1I8 / ASCC2_HUMAN
Protein Name Activating signal cointegrator 1 complex subunit 2
Gene Name Name: ASCC2
Synonyms:ASC1P100,RQT3;
Organism Homo sapiens (Human)

PRO ID PR:Q9H1I8
DAG View
PRO Name activating signal cointegrator 1 complex subunit 2 (human)
Definition An activating signal cointegrator 1 complex subunit 2 that is encoded in the genome of human.
Short Label hASCC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H1I8 (ASCC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
T233 Phosphorylation PhosphoSitePlus   UniProt 23186163
S235 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus   UniProt 24275569
T530 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
T564 Phosphorylation PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus   UniProt 24275569
K674 Ubiquitination PhosphoSitePlus
K699 Methylation PhosphoSitePlus
S706 Phosphorylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus   UniProt 20068231, 17924679
R715 Methylation PhosphoSitePlus
K730 Acetylation PhosphoSitePlus
T744 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S235 Phosphorylation HPRD 20068231
S713 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 N14 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S235 I235 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S313 F313 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S447 L447 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
S447 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S706 G706 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R715 Q715 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R715 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S751 N751 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]