iPTMnet Report for Q9H173 (SIL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H173 / SIL1_HUMAN
Protein Name Nucleotide exchange factor SIL1 precursor
Gene Name Name: SIL1
ORFNames:UNQ545/PRO836;
Organism Homo sapiens (Human)

PRO ID PR:Q9H173
DAG View
PRO Name nucleotide exchange factor SIL1 (human)
Definition A nucleotide exchange factor SIL1 that is encoded in the genome of human.
Short Label hSIL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H173 (SIL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 O-Glycosylation GlyGen 23301498, 31637018
T41 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K45 Ubiquitination PhosphoSitePlus
S46 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S47 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T48 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K54 Acetylation PhosphoSitePlus
T73 O-Glycosylation GlyGen 30459171, 25813380
T97 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
Y106 Phosphorylation PhosphoSitePlus
K109 Methylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
T127 O-Glycosylation GlyGen   PhosphoSitePlus 25813380
S128 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K132 Ubiquitination PhosphoSitePlus
S133 O-Glycosylation GlyGen 25813380
S147 Phosphorylation PhosphoSitePlus
N193 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...32125861, 24190977
K309 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
T400 Phosphorylation HPRD   PhosphoSitePlus 20068231
T406 Phosphorylation PhosphoSitePlus
T407 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T48 A48 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ]
S128 Y128 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S147 L147 Biomuta DOID:4159 / skin cancer [ cosmic ]
T407 I407 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]