iPTMnet Report for Q9H0W8 (SMG9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0W8 / SMG9_HUMAN
Protein Name Nonsense-mediated mRNA decay factor SMG9
Gene Name Name: SMG9
Synonyms:C19orf61;
Organism Homo sapiens (Human)

PRO ID PR:Q9H0W8
DAG View
PRO Name nonsense-mediated mRNA decay factor SMG9 (human)
Definition A nonsense-mediated mRNA decay factor SMG9 that is encoded in the genome of human.
Short Label hSMG9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0W8 (SMG9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 21406692, 20068231
S2 Phosphorylation PhosphoSitePlus   UniProt 23186163
S4 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S7 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 27920218, 20068231
Y12 Phosphorylation PhosphoSitePlus
K21 Methylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S32 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 20068231
Y41 Phosphorylation PhosphoSitePlus   RLIMS-P 21640080
S53 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
T64 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
T114 O-Glycosylation GlyGen 32938750, 35254053
T114 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
Y147 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
K170 Ubiquitination PhosphoSitePlus
R248 Methylation PhosphoSitePlus
C315 Methylation IEDB 31844290
K373 Ubiquitination PhosphoSitePlus
C380 Methylation IEDB 31844290
S451 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
K472 Ubiquitination PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 19651622, 18691976, 20058876, ...20068231
S4 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231
S7 Phosphorylation HPRD 19413330, 18691976, 17081983, ...20058876, 19651622, 20068231
S32 Phosphorylation HPRD 19651622, 18669648, 19664994, ...20068231
S53 Phosphorylation HPRD 19413330, 19651622, 18669648
Y147 Phosphorylation HPRD 15592455
S451 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 C4 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y12 C12 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S32 C32 Biomuta [ cosmic ]
R248 Q248 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ]
C315 W315 Biomuta DOID:10534 / stomach cancer [ cosmic ]
C315 Y315 Biomuta DOID:10283 / prostate cancer [ cosmic ]