iPTMnet Report for Q9H0W5 (CCDC8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0W5 / CCDC8_HUMAN
Protein Name Coiled-coil domain-containing protein 8
Gene Name Name: CCDC8
Organism Homo sapiens (Human)

PRO ID PR:Q9H0W5
DAG View
PRO Name coiled-coil domain-containing protein 8 (human)
Definition A coiled-coil domain-containing protein 8 that is encoded in the genome of human.
Short Label hCCDC8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0W5 (CCDC8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T87 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus   UniProt 21406692
S146 Phosphorylation PhosphoSitePlus   UniProt 21406692
Y197 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S261 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 19664994, ...19664995, 24275569
S273 Phosphorylation PhosphoSitePlus
S302 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
R320 Methylation PhosphoSitePlus
R344 Methylation PhosphoSitePlus
R445 Methylation PhosphoSitePlus
T477 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
K491 Methylation PhosphoSitePlus
T499 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S103 R103 Biomuta DOID:3571 / liver cancer [ cosmic ]
S146 N146 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R320 S320 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S487 L487 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S487 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]