iPTMnet Report for Q9H0M0 (WWP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0M0 / WWP1_HUMAN
Protein Name NEDD4-like E3 ubiquitin-protein ligase WWP1
Gene Name Name: WWP1
Organism Homo sapiens (Human)

PRO ID PR:Q9H0M0
DAG View
PRO Name NEDD4-like E3 ubiquitin-protein ligase WWP1 (human)
Definition A NEDD4-like E3 ubiquitin-protein ligase WWP1 that is encoded in the genome of human.
Short Label hWWP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0M0 (WWP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation PhosphoSitePlus
T23 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
T365 Phosphorylation PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
Y543 Phosphorylation PhosphoSitePlus
T575 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
Y639 Phosphorylation PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
K877 Ubiquitination PhosphoSitePlus
K900 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S59 Phosphorylation HPRD 18510355
S580 Phosphorylation HPRD 20068231
T822 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T3 A3 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T23 S23 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K89 E89 Biomuta DOID:4159 / skin cancer [ cosmic ]
K328 N328 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S580 F580 Biomuta DOID:4159 / skin cancer [ cosmic ]
K877 Q877 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K900 T900 Biomuta DOID:9256 / colorectal cancer [ icgc ]