iPTMnet Report for Q9H0L4 (CSTF2T)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0L4 / CSTFT_HUMAN
Protein Name Cleavage stimulation factor subunit 2 tau variant
Gene Name Name: CSTF2T
Synonyms:KIAA0689;
Organism Homo sapiens (Human)

PRO ID PR:Q9H0L4
DAG View
PRO Name cleavage stimulation factor subunit 2 tau variant (human)
Definition A cleavage stimulation factor subunit 2 tau variant that is encoded in the genome of human.
Short Label hCSTF2T
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0L4 (CSTF2T) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S3 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
R311 Methylation PhosphoSitePlus
R316 Methylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus   UniProt 23186163
R327 Methylation PhosphoSitePlus
R338 Methylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
R352 Methylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
R373 Methylation PhosphoSitePlus
R381 Methylation PhosphoSitePlus
R389 Methylation PhosphoSitePlus
R396 Methylation PhosphoSitePlus
R403 Methylation PhosphoSitePlus
R410 Methylation PhosphoSitePlus
R413 Methylation PhosphoSitePlus
C441 S-Nitrosylation dbSNO 26338901
R461 Methylation PhosphoSitePlus
S466 O-Glycosylation GlyGen 23301498, 28411811, 28510447, ...22121020, 29351928
S466 Phosphorylation PhosphoSitePlus
S467 O-Glycosylation GlyGen 23301498, 28411811, 28510447, ...22121020, 29351928
S467 Phosphorylation PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
S557 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
S561 Phosphorylation HPRD   PhosphoSitePlus 19664995
S563 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 15302935, 19664995, ...23186163
S567 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T570 Phosphorylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S205 Y205 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:2531 / hematologic cancer [ tcga ]
R311 I311 Biomuta DOID:363 / uterine cancer [ tcga ]
R316 H316 Biomuta DOID:1612 / breast cancer [ icgc, tcga ]
R327 * Biomuta DOID:4362 / cervical cancer [ icgc, tcga ]
R327 Q327 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R338 C338 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R338 H338 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
T346 A346 Biomuta DOID:363 / uterine cancer [ tcga ]
R373 H373 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R373 C373 Biomuta DOID:1909 / melanoma [ icgc, tcga ] DOID:3070 / malignant glioma [ tcga ]
R403 S403 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S557 C557 Biomuta DOID:363 / uterine cancer [ tcga ]
S567 N567 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T570 N570 Biomuta DOID:1793 / pancreatic cancer [ tcga ]