iPTMnet Report for Q9H0H0 (INTS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0H0 / INT2_HUMAN
Protein Name Integrator complex subunit 2
Gene Name Name: INTS2
Synonyms:KIAA1287;
Organism Homo sapiens (Human)

PRO ID PR:Q9H0H0
DAG View
PRO Name integrator complex subunit 2 (human)
Definition An integrator complex subunit 2 that is encoded in the genome of human.
Short Label hINTS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0H0 (INTS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K108 Ubiquitination PhosphoSitePlus
C226 Methylation IEDB 31844290
K231 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
T286 Phosphorylation PhosphoSitePlus
C300 Methylation IEDB 31844290
T353 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
C556 Methylation IEDB 31844290
K574 Ubiquitination PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
T746 Phosphorylation IEDB   PhosphoSitePlus 35494241
K750 Ubiquitination PhosphoSitePlus
K847 Ubiquitination PhosphoSitePlus
Y848 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T849 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T877 Phosphorylation PhosphoSitePlus
K897 Ubiquitination PhosphoSitePlus
K977 Ubiquitination PhosphoSitePlus
S1075 Phosphorylation PhosphoSitePlus
T1086 Phosphorylation PhosphoSitePlus
T1092 Phosphorylation PhosphoSitePlus
K1154 Ubiquitination PhosphoSitePlus
K1156 Ubiquitination PhosphoSitePlus
K1165 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K255 N255 Biomuta DOID:1612 / breast cancer [ icgc ]
K847 N847 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y848 C848 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1075 N1075 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1092 I1092 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]