iPTMnet Report for Q9H0F6 (SHARPIN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0F6 / SHRPN_HUMAN
Protein Name Sharpin
Gene Name Name: SHARPIN
Synonyms:SIPL1;ORFNames:PSEC0216;
Organism Homo sapiens (Human)

PRO ID PR:Q9H0F6
DAG View
PRO Name sharpin (human)
Definition A sharpin that is encoded in the genome of human.
Short Label hSHARPIN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0F6 (SHARPIN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R29 Methylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S165 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 33392484, 18669648, 23186163
T170 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K318 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S165 Phosphorylation HPRD 18669648
S312 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T170 R170 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S282 T282 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]