iPTMnet Report for Q9H0E2 (TOLLIP)
Protein Information
UniProt AC / UniProt ID | Q9H0E2 / TOLIP_HUMAN |
Protein Name | Toll-interacting protein |
Gene Name | Name: TOLLIP |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H0E2 |
PRO Name | Toll-interacting protein (human) |
Definition | A Toll-interacting protein that is encoded in the genome of human. |
Short Label | hTOLLIP |
Category | organism-gene |
Q9H0E2 (TOLLIP) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y13 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y45 | Phosphorylation | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y68 | Phosphorylation | score1 | PhosphoSitePlus | |||
T71 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y83 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y86 | Phosphorylation | score1 | PhosphoSitePlus | |||
K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
S171 | Phosphorylation | score1 | PhosphoSitePlus | |||
K235 | Acetylation | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | O75674 (TOM1L1) | S321 | Q9H0E2 (TOLLIP) | unknown | eFIP | 26899482 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S6 | N6 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |