iPTMnet Report for Q9H0B8 (CRISPLD2)
Protein Information
UniProt AC / UniProt ID | Q9H0B8 / CRLD2_HUMAN |
Protein Name | Cysteine-rich secretory protein LCCL domain-containing 2 precursor |
Gene Name | Name: CRISPLD2 Synonyms:CRISP11,LCRISP2;ORFNames:UNQ2914/PRO1156/PRO9783; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H0B8 |
PRO Name | cysteine-rich secretory protein LCCL domain-containing 2 (human) |
Definition | A cysteine-rich secretory protein LCCL domain-containing 2 that is encoded in the genome of human. |
Short Label | hCRISPLD2 |
Category | organism-gene |
Q9H0B8 (CRISPLD2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N41 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
T241 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T254 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
T285 | Phosphorylation | score1 | PhosphoSitePlus | |||
T292 | Phosphorylation | score1 | PhosphoSitePlus | |||
T322 | Phosphorylation | score1 | PhosphoSitePlus | |||
S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y373 | Phosphorylation | score1 | PhosphoSitePlus | |||
S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
S382 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y468 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T254 | M254 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T322 | S322 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
Y373 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
Y468 | C468 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |