iPTMnet Report for Q9H0A0 (NAT10)
Protein Information
| UniProt AC / UniProt ID | Q9H0A0 / NAT10_HUMAN |
| Protein Name | RNA cytidine acetyltransferase |
| Gene Name | Name: NAT10 Synonyms:ALP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H0A0 |
| PRO Name | RNA cytidine acetyltransferase (human) |
| Definition | An RNA cytidine acetyltransferase that is encoded in the genome of human. |
| Short Label | hNAT10 |
| Category | organism-gene |
Q9H0A0 (NAT10) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R32 | Methylation | score1 | PhosphoSitePlus | |||
| C58 | Methylation | score1 | IEDB | 31844290 | ||
| K60 | Acetylation | score1 | PhosphoSitePlus | |||
| K61 | Acetylation | score1 | PhosphoSitePlus | |||
| K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S67 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C105 | Methylation | score1 | IEDB | 31844290 | ||
| T137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T164 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K195 | Methylation | score1 | PhosphoSitePlus | |||
| T223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K266 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y416 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K426 | Acetylation | score4 | PhosphoSitePlus UniProt | 19608861, 27993683 | ||
| K426 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S438 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K447 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T493 | O-Glycosylation | score1 | GlyGen | 30379171, 33214551, 28510447, ... | ||
| K520 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S589 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S593 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K599 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y635 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T666 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S679 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T686 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K689 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T716 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T741 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S809 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y820 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K823 | Acetylation | score1 | PhosphoSitePlus | |||
| K823 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K904 | Acetylation | score1 | PhosphoSitePlus | |||
| K904 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T929 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T932 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S934 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| K942 | Acetylation | score1 | PhosphoSitePlus | |||
| K942 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K947 | Acetylation | score1 | PhosphoSitePlus | |||
| K956 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S957 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y963 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K978 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S984 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S987 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S990 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S190 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S435 | Phosphorylation | score0 | HPRD | 19007248, 19691289 | ||
| T443 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T450 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S589 | Phosphorylation | score0 | HPRD | 19691289 | ||
| S809 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T932 | Phosphorylation | score0 | HPRD | 19007248 | ||
| S934 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 18452278, ... | ||
| S984 | Phosphorylation | score0 | HPRD | 18669648, 19691289, 20068231 | ||
| S987 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S990 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R32 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| R32 | Q32 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K61 | R61 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S156 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K274 | N274 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| Y416 | C416 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S435 | N435 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| T450 | M450 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S679 | N679 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
| S957 | N957 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y963 | C963 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S984 | * | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S984 | L984 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View