iPTMnet Report Q9H093 NUAK2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9H093 / NUAK2_HUMAN
Protein Name	NUAK family SNF1-like kinase 2
Gene Name	Name: NUAK2 Synonyms:OMPHK2,SNARK;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9H093 DAG View
PRO Name	NUAK family SNF1-like kinase 2 (human)
Definition	A NUAK family SNF1-like kinase 2 that is encoded in the genome of human.
Short Label	hNUAK2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9H093 (NUAK2) as Substrate

Q9H093

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	M1	Acetylation		score1	UniProt	22814378
	S30	Phosphorylation		score1	PhosphoSitePlus
	T58	Phosphorylation		score1	PhosphoSitePlus
	K81	Ubiquitination		score1	PhosphoSitePlus
	Y138	Phosphorylation		score1	PhosphoSitePlus
	Y140	Phosphorylation		score1	PhosphoSitePlus
	S142	Phosphorylation		score1	PhosphoSitePlus
	T208	Phosphorylation	Q15831 (STK11)	score4	neXtProt phospho.ELM PhosphoSitePlus Signor UniProt	32845958, 14976552
	Y267	Phosphorylation		score1	PhosphoSitePlus
	S435	Phosphorylation		score2	PhosphoSitePlus UniProt	19369195
	S462	Phosphorylation		score1	PhosphoSitePlus
	K487	Ubiquitination		score1	PhosphoSitePlus
	S523	Phosphorylation		score2	PhosphoSitePlus UniProt	19369195
	S544	Phosphorylation		score2	PhosphoSitePlus UniProt	19369195
	S547	Phosphorylation		score2	PhosphoSitePlus UniProt	19369195
	S553	Phosphorylation		score1	PhosphoSitePlus

Q9H093 (NUAK2) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	O95835 (LATS1)	S464	score3	PhosphoSitePlus Signor	19927127

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T208	K208	Biomuta		DOID:263 / kidney cancer [ icgc ]
S547	R547	Biomuta		DOID:1324 / lung cancer [ icgc ]