iPTMnet Report for Q9H089 (LSG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H089 / LSG1_HUMAN
Protein Name Large subunit GTPase 1 homolog
Gene Name Name: LSG1
Organism Homo sapiens (Human)

PRO ID PR:Q9H089
DAG View
PRO Name large subunit GTPase 1 homolog (human)
Definition A large subunit GTPase 1 that is encoded in the genome of human.
Short Label hLSG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H089 (LSG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R5 Methylation PhosphoSitePlus
S11 Phosphorylation HPRD   PhosphoSitePlus 18212344
R14 Methylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
Y43 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus   UniProt 23186163
S97 Phosphorylation PhosphoSitePlus   UniProt 23186163
K102 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
S252 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
S279 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
K383 Acetylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
S413 O-Glycosylation GlyGen 30379171, 28510447
S413 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
T421 Phosphorylation HPRD 20068231
T493 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
Y615 Phosphorylation PhosphoSitePlus
Y653 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 C32 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S32 F32 Biomuta DOID:4159 / skin cancer [ cosmic ]
K151 N151 Biomuta DOID:1324 / lung cancer [ cosmic ]
S252 F252 Biomuta DOID:4159 / skin cancer [ cosmic ]
S279 F279 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T320 A320 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S413 C413 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
K569 R569 Biomuta DOID:1319 / brain cancer [ cosmic ]