iPTMnet Report for Q9H081 (MIS12)
Protein Information
| UniProt AC / UniProt ID | Q9H081 / MIS12_HUMAN |
| Protein Name | Protein MIS12 homolog |
| Gene Name | Name: MIS12 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H081 |
| PRO Name | protein MIS12 homolog (human) |
| Definition | A protein MIS12 that is encoded in the genome of human. |
| Short Label | hMIS12 |
| Category | organism-gene |
DAG ViewQ9H081 (MIS12) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K151 | Ubiquitination | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q96BT3 (CENPT) | S201 | Q9H081 (MIS12) | unknown | eFIP | 28012276 | |
| Phosphorylation | Q9Y2Z0 (SUGT1) | S331 | Q9H081 (MIS12) | increased_association | eFIP | 22869522 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K146 | E146 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
