Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H013 / ADA19_HUMAN
Protein Name Disintegrin and metalloproteinase domain-containing protein 19 precursor
Gene Name Name: ADAM19
Synonyms:MLTNB;ORFNames:FKSG34;
Organism Homo sapiens (Human)

PRO ID PR:Q9H013
DAG View
PRO Name disintegrin and metalloproteinase domain-containing protein 19 (human)
Definition A disintegrin and metalloproteinase domain-containing protein 19 that is encoded in the genome of human.
Short Label hADAM19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H013 (ADAM19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T183 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T191 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T194 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
Y248 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
T769 Phosphorylation PhosphoSitePlus
T779 Phosphorylation PhosphoSitePlus
S802 Phosphorylation PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus
S830 Phosphorylation PhosphoSitePlus
S831 Phosphorylation PhosphoSitePlus
S872 Phosphorylation PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus
K909 Ubiquitination PhosphoSitePlus
R921 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T779 Phosphorylation HPRD 19664994
K917 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K288 R288 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K741 T741 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T769 M769 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S818 F818 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S830 L830 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
S830 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S892 F892 Biomuta DOID:4159 / skin cancer [ icgc ]
K909 N909 Biomuta DOID:10534 / stomach cancer [ cosmic ]