iPTMnet Report for Q9GZZ1 (NAA50)
Protein Information
UniProt AC / UniProt ID | Q9GZZ1 / NAA50_HUMAN |
Protein Name | N-alpha-acetyltransferase 50 |
Gene Name | Name: NAA50 Synonyms:MAK3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9GZZ1 |
PRO Name | N-alpha-acetyltransferase 50 (human) |
Definition | An N-alpha-acetyltransferase 50 that is encoded in the genome of human. |
Short Label | hNAA50 |
Category | organism-gene |
Q9GZZ1 (NAA50) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K2 | Ubiquitination | score1 | PhosphoSitePlus | |||
T12 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y31 | Phosphorylation | score1 | PhosphoSitePlus | |||
K34 | Acetylation | Q9GZZ1 (NAA50) | score4 | PhosphoSitePlus UniProt | 19608861, 19744929 | |
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
K37 | Acetylation | Q9GZZ1 (NAA50) | score4 | PhosphoSitePlus UniProt | 19608861, 19744929 | |
K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y73 | Phosphorylation | score1 | PhosphoSitePlus | |||
C79 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y110 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 15592455 | ||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
K140 | Acetylation | Q9GZZ1 (NAA50) | score3 | PhosphoSitePlus UniProt | 19744929 | |
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
K152 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
T167 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T12 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S30 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y31 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y110 | Phosphorylation | score0 | HPRD | 15592455 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K34 | Acetylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
K38 | Ubiquitination | score1 | PhosphoSitePlus |
Q9GZZ1 (NAA50) as PTM Enzyme
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S30 | R30 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
C79 | Y79 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
K126 | Q126 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K135 | N135 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K140 | T140 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |