iPTMnet Report for Q9GZZ1 (NAA50)
Protein Information
| UniProt AC / UniProt ID | Q9GZZ1 / NAA50_HUMAN |
| Protein Name | N-alpha-acetyltransferase 50 |
| Gene Name | Name: NAA50 Synonyms:MAK3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9GZZ1 |
| PRO Name | N-alpha-acetyltransferase 50 (human) |
| Definition | An N-alpha-acetyltransferase 50 that is encoded in the genome of human. |
| Short Label | hNAA50 |
| Category | organism-gene |
Q9GZZ1 (NAA50) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K2 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T12 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
| K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K34 | Acetylation | Q9GZZ1 (NAA50) | score4 | PhosphoSitePlus UniProt | 19608861, 19744929 | |
| K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K37 | Acetylation | Q9GZZ1 (NAA50) | score4 | PhosphoSitePlus UniProt | 19608861, 19744929 | |
| K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C79 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y110 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 15592455 | ||
| K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K140 | Acetylation | Q9GZZ1 (NAA50) | score3 | PhosphoSitePlus UniProt | 19744929 | |
| K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K152 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T167 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T12 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S30 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y31 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y110 | Phosphorylation | score0 | HPRD | 15592455 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K34 | Acetylation | score1 | PhosphoSitePlus | |||
| K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K38 | Ubiquitination | score1 | PhosphoSitePlus |
Q9GZZ1 (NAA50) as PTM Enzyme
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S30 | R30 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| C79 | Y79 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| K126 | Q126 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K135 | N135 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K140 | T140 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View