iPTMnet Report for Q9GZV9 (FGF23)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9GZV9 / FGF23_HUMAN
Protein Name Fibroblast growth factor 23 precursor
Gene Name Name: FGF23
Synonyms:HYPF;ORFNames:UNQ3027/PRO9828;
Organism Homo sapiens (Human)

PRO ID PR:Q9GZV9
DAG View
PRO Name fibroblast growth factor 23 (human)
Definition A fibroblast growth factor 23 that is encoded in the genome of human.
Short Label hFGF23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9GZV9 (FGF23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y51 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
T171 O-Glycosylation GlyGen   UniProt 31932717
T178 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 16638743, 31932717
S180 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor   UniProt 24706917, 31932717
S180 Phosphorylation Q8IXL6 (FAM20C) PhosphoSitePlus   Signor 24706917
S207 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y154 H154 Biomuta DOID:3571 / liver cancer [ cosmic ]
T171 I171 Biomuta DOID:4159 / skin cancer [ cosmic ]
T178 I178 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S180 R180 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S207 L207 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]