iPTMnet Report for Q9GZV4 (EIF5A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9GZV4 / IF5A2_HUMAN
Protein Name Eukaryotic translation initiation factor 5A-2
Gene Name Name: EIF5A2
Organism Homo sapiens (Human)

PRO ID PR:Q9GZV4
DAG View
PRO Name eukaryotic translation initiation factor 5A-2 (human)
Definition A eukaryotic translation initiation factor 5A-2 that is encoded in the genome of human.
Short Label hEIF5A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9GZV4 (EIF5A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K27 Acetylation PhosphoSitePlus
K27 Sumoylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K34 Sumoylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K39 Acetylation PhosphoSitePlus
K39 Sumoylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
K67 Acetylation PhosphoSitePlus
K67 Sumoylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
K68 Methylation PhosphoSitePlus
K68 Sumoylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
Y69 Phosphorylation PhosphoSitePlus
C73 S-Nitrosylation dbSNO 2212679, 22126794
K85 Acetylation PhosphoSitePlus
K85 Sumoylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S46 A46 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K68 T68 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]