iPTMnet Report for Q9GZU1 (MCOLN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9GZU1 / MCLN1_HUMAN
Protein Name Mucolipin-1
Gene Name Name: MCOLN1
Synonyms:ML4,TRPML1;ORFNames:MSTP080;
Organism Homo sapiens (Human)

PRO ID PR:Q9GZU1
DAG View
PRO Name mucolipin-1 (human)
Definition A mucolipin-1 that is encoded in the genome of human.
Short Label hMCOLN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9GZU1 (MCOLN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
T34 Phosphorylation HPRD   PhosphoSitePlus 15345747
K46 Ubiquitination PhosphoSitePlus
Y47 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
N159 N-Glycosylation GlyGen 24190977
N230 N-Glycosylation GlyGen   UniProt 19159218
S244 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S557 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17988215
S559 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor   UniProt 17988215
S562 Phosphorylation PhosphoSitePlus
S572 Phosphorylation RLIMS-P 26195823, 31112550
S576 Phosphorylation PhosphoSitePlus   RLIMS-P 26195823, 31112550


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K46 R46 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S576 L576 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]