Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9GZQ8 / MLP3B_HUMAN
Protein Name Microtubule-associated proteins 1A/1B light chain 3B precursor
Gene Name Name: MAP1LC3B
Synonyms:MAP1ALC3;
Organism Homo sapiens (Human)

PRO ID PR:Q9GZQ8
DAG View
PRO Name microtubule-associated proteins 1A/1B light chain 3B (human)
Definition A microtubule-associated proteins 1A/1B light chain 3B that is encoded in the genome of human.
Short Label hMAP1LC3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9GZQ8 (MAP1LC3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
T6 Phosphorylation PhosphoSitePlus
R21 Methylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q8IVP5 (FUNDC1) Y18 Q9GZQ8 (MAP1LC3B) unknown eFIP 27757847


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R21 G21 Biomuta DOID:1909 / melanoma [ tcga ]
R21 * Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R21 Q21 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K65 N65 Biomuta DOID:3571 / liver cancer [ icgc ]
K65 E65 Biomuta DOID:1909 / melanoma [ cosmic ]