iPTMnet Report for Q9GZP0 (PDGFD)
Protein Information
| UniProt AC / UniProt ID | Q9GZP0 / PDGFD_HUMAN |
| Protein Name | Platelet-derived growth factor D precursor |
| Gene Name | Name: PDGFD Synonyms:IEGF,SCDGFB;ORFNames:MSTP036,UNQ1899/PRO4345; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9GZP0 |
| PRO Name | platelet-derived growth factor D (human) |
| Definition | A platelet-derived growth factor D that is encoded in the genome of human. |
| Short Label | hPDGFD |
| Category | organism-gene |
Q9GZP0 (PDGFD) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T24 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S189 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S197 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T201 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y240 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T243 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T273 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y327 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S189 | C189 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| S197 | T197 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T201 | M201 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
| Y226 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| Y240 | C240 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T243 | S243 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
DAG View