iPTMnet Report for Q9C0K0 (BCL11B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0K0 / BC11B_HUMAN
Protein Name B-cell lymphoma/leukemia 11B
Gene Name Name: BCL11B
Synonyms:CTIP2,RIT1;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0K0
DAG View
PRO Name B-cell lymphoma/leukemia 11B (human)
Definition A B-cell lymphoma/leukemia 11B that is encoded in the genome of human.
Short Label hBCL11B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0K0 (BCL11B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus   UniProt 19690332
K108 Ubiquitination PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus   UniProt 19690332
S129 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus   UniProt 19690332
S257 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus   UniProt 19690332
R262 Methylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus   UniProt 19690332
S286 Phosphorylation PhosphoSitePlus
R293 Methylation PhosphoSitePlus
R300 Methylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
R322 Methylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus   UniProt 19690332
S364 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
T376 Phosphorylation PhosphoSitePlus   UniProt 19690332
S381 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
S398 Phosphorylation PhosphoSitePlus   UniProt 19690332
S401 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus   UniProt 19690332
K427 Ubiquitination PhosphoSitePlus
K434 Acetylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
T450 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus   UniProt 19690332
S488 Phosphorylation PhosphoSitePlus   UniProt 19690332
S493 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus   UniProt 19690332
S497 Phosphorylation PhosphoSitePlus   UniProt 19690332
T502 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
T662 Phosphorylation PhosphoSitePlus
R671 Methylation PhosphoSitePlus
K672 Ubiquitination PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus   UniProt 19690332
K686 Ubiquitination PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
K723 Ubiquitination PhosphoSitePlus
T730 Phosphorylation PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
T739 Phosphorylation PhosphoSitePlus
S749 Phosphorylation PhosphoSitePlus
R751 Methylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
T754 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus   UniProt 19690332
S768 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
T776 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
T797 Phosphorylation PhosphoSitePlus
K803 Ubiquitination PhosphoSitePlus
K806 Ubiquitination PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
T819 Phosphorylation PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
K844 Ubiquitination PhosphoSitePlus
K851 Acetylation PhosphoSitePlus   UniProt 19608861
K851 Ubiquitination PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
K887 Sumoylation PhosphoSitePlus
K887 Ubiquitination PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S753 Phosphorylation HPRD 20058876
Site PTM Type PTM Enzyme Score Source PMID
K137 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
S682 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 F13 Biomuta DOID:4159 / skin cancer [ cosmic ]
K95 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S97 N97 Biomuta DOID:4159 / skin cancer [ cosmic ]
K108 R108 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S129 L129 Biomuta [ cosmic ]
S257 N257 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T260 M260 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R262 Q262 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S277 Y277 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S286 C286 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]
R293 H293 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R300 L300 Biomuta DOID:1324 / lung cancer [ cosmic ]
R322 H322 Biomuta DOID:3571 / liver cancer [ cosmic ]
S358 A358 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S364 L364 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S398 G398 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S398 C398 Biomuta DOID:3119 / gastrointestinal system cancer [ cosmic ]
S405 N405 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T406 M406 Biomuta DOID:263 / kidney cancer [ cosmic ]
K434 N434 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T450 A450 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T450 M450 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S465 L465 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K469 T469 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K469 N469 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K480 T480 Biomuta DOID:3571 / liver cancer [ cosmic ]
S488 T488 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S488 F488 Biomuta DOID:4159 / skin cancer [ cosmic ]
S493 L493 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S497 F497 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S497 P497 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S560 L560 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R671 H671 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R671 C671 Biomuta DOID:1324 / lung cancer [ cosmic ]
K689 N689 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S765 L765 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S768 C768 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S789 F789 Biomuta DOID:1319 / brain cancer [ icgc ]
K790 N790 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T797 M797 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K838 T838 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K887 N887 Biomuta DOID:363 / uterine cancer [ icgc ]