iPTMnet Report for Q9C0J8 (WDR33)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0J8 / WDR33_HUMAN
Protein Name pre-mRNA 3' end processing protein WDR33
Gene Name Name: WDR33
Synonyms:WDC146;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0J8
DAG View
PRO Name pre-mRNA 3' end processing protein WDR33 (human)
Definition A pre-mRNA 3' end processing protein WDR33 that is encoded in the genome of human.
Short Label hWDR33
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0J8 (WDR33) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 21406692, 20068231
S7 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
R10 Methylation PhosphoSitePlus
R16 Methylation PhosphoSitePlus
R23 Methylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
R29 Methylation PhosphoSitePlus
K46 Acetylation PhosphoSitePlus   UniProt 19608861
K46 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
C120 Methylation IEDB 31844290
K196 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K264 Acetylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
T290 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
Y496 Phosphorylation PhosphoSitePlus
K498 Acetylation PhosphoSitePlus
K530 Sumoylation PhosphoSitePlus
Y550 Phosphorylation PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
R782 Methylation PhosphoSitePlus   UniProt 24129315
R791 Methylation PhosphoSitePlus
R811 Methylation PhosphoSitePlus
R828 Methylation PhosphoSitePlus
R834 Methylation PhosphoSitePlus
T907 Phosphorylation PhosphoSitePlus
R915 Methylation PhosphoSitePlus   UniProt 24129315
R942 Methylation PhosphoSitePlus
S971 Phosphorylation PhosphoSitePlus
R991 Methylation PhosphoSitePlus
R1030 Methylation PhosphoSitePlus
R1035 Methylation PhosphoSitePlus
R1047 Methylation PhosphoSitePlus
R1067 Methylation PhosphoSitePlus
R1071 Methylation PhosphoSitePlus
R1106 Methylation PhosphoSitePlus
R1111 Methylation PhosphoSitePlus
R1121 Methylation PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus
R1144 Methylation PhosphoSitePlus
R1146 Methylation PhosphoSitePlus
T1166 Phosphorylation PhosphoSitePlus
S1181 Phosphorylation PhosphoSitePlus
S1210 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 24275569
S1213 Phosphorylation PhosphoSitePlus
S1217 Phosphorylation PhosphoSitePlus
S1218 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S1219 Phosphorylation PhosphoSitePlus
R1233 Methylation PhosphoSitePlus
S1254 Phosphorylation PhosphoSitePlus
R1257 Methylation PhosphoSitePlus
R1262 Methylation PhosphoSitePlus
R1270 Methylation PhosphoSitePlus
R1276 Methylation PhosphoSitePlus
S1277 Phosphorylation PhosphoSitePlus
S1278 Phosphorylation PhosphoSitePlus
S1279 Phosphorylation PhosphoSitePlus
R1290 Methylation PhosphoSitePlus
T1302 Phosphorylation PhosphoSitePlus
S1304 Phosphorylation PhosphoSitePlus
R1305 Methylation PhosphoSitePlus
R1308 Methylation PhosphoSitePlus
R1315 Methylation PhosphoSitePlus   UniProt 24129315
R1325 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 19413330, 19651622, 20058876, ...17081983, 20068231
T277 Phosphorylation HPRD 20068231
S1139 Phosphorylation HPRD 20068231
S1210 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S1213 Phosphorylation HPRD 20068231
S1217 Phosphorylation HPRD 20068231
S1277 Phosphorylation HPRD 18452278
S1279 Phosphorylation HPRD 18707149
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 19413330, 19651622, 20058876, ...17081983, 20068231
S217 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 19413330, 19651622, 20058876, ...17081983, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
A2 P2 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R10 C10 Biomuta DOID:1324 / lung cancer [ cosmic ]
R16 K16 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R23 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2021 / placenta cancer [ cosmic ]
R23 Q23 Biomuta DOID:363 / uterine cancer [ icgc ]
K119 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K196 R196 Biomuta DOID:1324 / lung cancer [ cosmic ]
K196 N196 Biomuta DOID:363 / uterine cancer [ icgc ]
K202 T202 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K216 T216 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K288 I288 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S764 F764 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R782 S782 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R791 Q791 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R834 Q834 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R834 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T907 M907 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R915 W915 Biomuta DOID:1319 / brain cancer [ icgc ]
R991 L991 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R991 W991 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R1030 H1030 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R1030 C1030 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1035 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R1047 * Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R1111 S1111 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R1121 K1121 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1144 L1144 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1144 Q1144 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1144 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
S1210 Y1210 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1210 F1210 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S1210 C1210 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1217 F1217 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1217 P1217 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1218 F1218 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R1233 H1233 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:5158 / pleural cancer [ cosmic ]
R1233 P1233 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1254 F1254 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R1257 Q1257 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R1257 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R1262 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R1262 Q1262 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R1276 H1276 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
R1276 C1276 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R1276 P1276 Biomuta DOID:184 / bone cancer [ cosmic ]
S1277 C1277 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1279 C1279 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1304 Y1304 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1305 Q1305 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1305 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
R1308 Q1308 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
R1315 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
R1325 K1325 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1325 S1325 Biomuta DOID:1324 / lung cancer [ cosmic ]