iPTMnet Report for Q9C0H2 (TTYH3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0H2 / TTYH3_HUMAN
Protein Name Protein tweety homolog 3
Gene Name Name: TTYH3
Synonyms:KIAA1691;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0H2
DAG View
PRO Name protein tweety homolog 3 (human)
Definition A protein tweety homolog 3 that is encoded in the genome of human.
Short Label hTTYH3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0H2 (TTYH3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N144 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K310 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
N351 N-Glycosylation GlyGen   UniProt 15010458, 24190977
C407 Methylation IEDB 31844290
S437 Phosphorylation PhosphoSitePlus
Y439 Phosphorylation PhosphoSitePlus
S452 Phosphorylation IEDB 35494241
T472 Phosphorylation PhosphoSitePlus
Y474 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
Y509 Phosphorylation PhosphoSitePlus
T512 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus   UniProt 21406692
Site PTM Type PTM Enzyme Score Source PMID
Y509 Phosphorylation HPRD 20068231
T512 Phosphorylation HPRD 20068231
S519 Phosphorylation HPRD 20068231
S520 Phosphorylation HPRD 19651622, 18578522
S522 Phosphorylation HPRD 19651622, 18578522, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N351 D351 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y509 S509 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
T512 R512 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]