iPTMnet Report for Q9C0E8 (LNPK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0E8 / LNP_HUMAN
Protein Name Endoplasmic reticulum junction formation protein lunapark
Gene Name Name: LNPK
Synonyms:KIAA1715;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0E8
DAG View
PRO Name endoplasmic reticulum junction formation protein lunapark (human)
Definition An endoplasmic reticulum junction formation protein lunapark that is encoded in the genome of human.
Short Label hLNPK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0E8 (LNPK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 24223779, 20213681
S13 Phosphorylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
S114 Phosphorylation UniProt 27619977
K118 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
K145 Acetylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S153 Phosphorylation UniProt 27619977
S177 Phosphorylation PhosphoSitePlus   UniProt 27619977, 20068231
T179 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus   UniProt 18691976, 27619977, 20068231
S194 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 24275569, ...27619977, 20068231
S202 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus   UniProt 27619977
T213 Phosphorylation PhosphoSitePlus   UniProt 23186163
S217 Phosphorylation PhosphoSitePlus   UniProt 27619977, 23186163, 24275569
S227 Phosphorylation PhosphoSitePlus   UniProt 27619977
Y293 Phosphorylation PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus   UniProt 18691976, 27619977
K324 Ubiquitination PhosphoSitePlus
S353 Phosphorylation UniProt 27619977
S384 Phosphorylation PhosphoSitePlus   UniProt 27619977, 24275569
S386 Phosphorylation PhosphoSitePlus
S421 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S424 Phosphorylation phospho.ELM 17081983
Site PTM Type PTM Enzyme Score Source PMID
S177 Phosphorylation HPRD 19651622, 18691976, 18578522, ...20068231
T179 Phosphorylation HPRD 18578522
S182 Phosphorylation HPRD 19651622, 18691976, 20068231
S194 Phosphorylation HPRD 19651622, 18691976, 20068231
T213 Phosphorylation HPRD 18691976
S227 Phosphorylation HPRD 20068231, 17924679
S321 Phosphorylation HPRD 18691976
S384 Phosphorylation HPRD 19651622
S421 Phosphorylation HPRD 17081983, 20068231
S424 Phosphorylation HPRD 17081983, 20068231
T426 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K113 Q113 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S114 F114 Biomuta DOID:4159 / skin cancer [ cosmic ]
K118 T118 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K144 E144 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K144 N144 Biomuta DOID:363 / uterine cancer [ icgc ]
S182 N182 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S194 C194 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S217 L217 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S421 T421 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S421 N421 Biomuta DOID:1324 / lung cancer [ cosmic ]
T426 M426 Biomuta DOID:4606 / bile duct cancer [ cosmic ]