iPTMnet Report for Q9C0B9 (ZCCHC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0B9 / ZCHC2_HUMAN
Protein Name Zinc finger CCHC domain-containing protein 2
Gene Name Name: ZCCHC2
Synonyms:C18orf49;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0B9
DAG View
PRO Name zinc finger CCHC domain-containing protein 2 (human)
Definition A zinc finger CCHC domain-containing protein 2 that is encoded in the genome of human.
Short Label hZCCHC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0B9 (ZCCHC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K151 Ubiquitination PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus   UniProt 21406692
S273 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T605 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
T747 O-Glycosylation GlyGen 28657654, 35254053
S754 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S873 Phosphorylation PhosphoSitePlus
S1121 O-Glycosylation GlyGen 28657654, 35254053
S1150 Phosphorylation PhosphoSitePlus
T1158 Phosphorylation PhosphoSitePlus
Y1159 Phosphorylation PhosphoSitePlus
Y1163 Phosphorylation PhosphoSitePlus
T1173 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S489 Phosphorylation HPRD 17081983
S490 Phosphorylation HPRD 17081983
S493 Phosphorylation HPRD 17081983
S494 Phosphorylation HPRD 17081983
S649 Phosphorylation HPRD 19651622
S652 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S182 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S422 F422 Biomuta DOID:4159 / skin cancer [ cosmic ]
S479 C479 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S623 C623 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S649 I649 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S652 G652 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S767 L767 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1173 M1173 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ icgc ]