Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C099 / LRCC1_HUMAN
Protein Name Leucine-rich repeat and coiled-coil domain-containing protein 1
Gene Name Name: LRRCC1
Synonyms:CLERC,KIAA1764;
Organism Homo sapiens (Human)

PRO ID PR:Q9C099
DAG View
PRO Name leucine-rich repeat and coiled-coil domain-containing protein 1 (human)
Definition A leucine-rich repeat and coiled-coil domain-containing protein 1 that is encoded in the genome of human.
Short Label hLRRCC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C099 (LRRCC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K296 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
Y561 Phosphorylation PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
T693 Phosphorylation PhosphoSitePlus
K697 Ubiquitination PhosphoSitePlus
K708 Ubiquitination PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
T713 Phosphorylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
K803 Ubiquitination PhosphoSitePlus
K836 Ubiquitination PhosphoSitePlus
K846 Ubiquitination PhosphoSitePlus
K852 Ubiquitination PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
K898 Ubiquitination PhosphoSitePlus
K906 Acetylation PhosphoSitePlus
K910 Ubiquitination PhosphoSitePlus
K947 Ubiquitination PhosphoSitePlus
K952 Ubiquitination PhosphoSitePlus
S955 Phosphorylation PhosphoSitePlus
K961 Methylation PhosphoSitePlus
K982 Ubiquitination PhosphoSitePlus
S988 O-Glycosylation GlyGen 30379171
S988 Phosphorylation PhosphoSitePlus
K998 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T713 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K461 N461 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K476 N476 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K476 Q476 Biomuta DOID:4159 / skin cancer [ cosmic ]
K501 R501 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K501 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y561 F561 Biomuta [ cosmic ]
T693 A693 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K710 E710 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S757 L757 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K803 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K846 M846 Biomuta DOID:4159 / skin cancer [ cosmic ]
K906 R906 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S955 I955 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]