iPTMnet Report for Q9C093 (SPEF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C093 / SPEF2_HUMAN
Protein Name Sperm flagellar protein 2
Gene Name Name: SPEF2
Synonyms:KIAA1770,KPL2;
Organism Homo sapiens (Human)

PRO ID PR:Q9C093
DAG View
PRO Name sperm flagellar protein 2 (human)
Definition A sperm flagellar protein 2 that is encoded in the genome of human.
Short Label hSPEF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C093 (SPEF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K177 Ubiquitination PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
K885 Acetylation PhosphoSitePlus
K891 Acetylation PhosphoSitePlus
K892 Acetylation PhosphoSitePlus
K963 Acetylation PhosphoSitePlus
K969 Acetylation PhosphoSitePlus
K977 Acetylation PhosphoSitePlus
K982 Acetylation PhosphoSitePlus
K982 Ubiquitination PhosphoSitePlus
K1697 Acetylation PhosphoSitePlus
K1706 Acetylation PhosphoSitePlus
K1726 Acetylation PhosphoSitePlus
Y1750 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K236 E236 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K891 N891 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K969 R969 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]