Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C075 / K1C23_HUMAN
Protein Name Keratin, type I cytoskeletal 23
Gene Name Name: KRT23
Organism Homo sapiens (Human)

PRO ID PR:Q9C075
DAG View
PRO Name keratin, type I cytoskeletal 23 (human)
Definition A keratin, type I cytoskeletal 23 that is encoded in the genome of human.
Short Label hKRT23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C075 (KRT23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
T33 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
T48 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
R179 Methylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
Y354 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 R8 Biomuta DOID:3571 / liver cancer [ tcga ]
S44 F44 Biomuta DOID:1909 / melanoma [ tcga ] DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T48 I48 Biomuta DOID:3070 / malignant glioma [ icgc ]
T48 A48 Biomuta DOID:2531 / hematologic cancer [ tcga ]
K106 Q106 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
R179 * Biomuta DOID:10534 / stomach cancer [ tcga ] DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
Y354 C354 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]