iPTMnet Report for Q9C073 (FAM117A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C073 / F117A_HUMAN
Protein Name Protein FAM117A
Gene Name Name: FAM117A
Organism Homo sapiens (Human)

PRO ID PR:Q9C073
DAG View
PRO Name protein FAM117A (human)
Definition A protein FAM117A that is encoded in the genome of human.
Short Label hFAM117A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C073 (FAM117A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R9 Methylation PhosphoSitePlus
R18 Methylation PhosphoSitePlus
R25 Methylation PhosphoSitePlus
R26 Methylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S36 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus   UniProt 23186163
C70 Methylation IEDB 31844290
S91 Phosphorylation PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
K153 Acetylation PhosphoSitePlus
K159 Acetylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
R187 Methylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S196 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus   UniProt 23186163
S207 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 19690332
C255 Methylation IEDB 31844290
S277 Phosphorylation PhosphoSitePlus
T299 Phosphorylation PhosphoSitePlus   UniProt 23186163
S306 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus   UniProt 23186163
S355 Phosphorylation PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S145 Phosphorylation HPRD 19651622
S213 Phosphorylation HPRD 19651622, 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R187 W187 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
R187 Q187 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S201 F201 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S207 I207 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S277 Y277 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S306 F306 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T354 M354 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S413 N413 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]