iPTMnet Report for Q9C037 (TRIM4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C037 / TRIM4_HUMAN
Protein Name E3 ubiquitin-protein ligase TRIM4
Gene Name Name: TRIM4
Synonyms:RNF87;
Organism Homo sapiens (Human)

PRO ID PR:Q9C037
DAG View
PRO Name E3 ubiquitin-protein ligase TRIM4 (human)
Definition An E3 ubiquitin-protein ligase TRIM4 that is encoded in the genome of human.
Short Label hTRIM4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C037 (TRIM4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S56 Phosphorylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
K173 Acetylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
C397 Methylation IEDB 31844290
T405 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S129 Phosphorylation PhosphoSitePlus
Y130 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S56 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y282 H282 Biomuta DOID:4159 / skin cancer [ cosmic ]
S343 L343 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]