iPTMnet Report for Q9C004 (SPRY4)
Protein Information
| UniProt AC / UniProt ID | Q9C004 / SPY4_HUMAN |
| Protein Name | Protein sprouty homolog 4 |
| Gene Name | Name: SPRY4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9C004 |
| PRO Name | protein sprouty homolog 4 (human) |
| Definition | A protein sprouty homolog 4 that is encoded in the genome of human. |
| Short Label | hSPRY4 |
| Category | organism-gene |
DAG ViewQ9C004 (SPRY4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22223895 | ||
| T12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y52 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 15584898 | ||
| T77 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S125 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18669648 | ||
| K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K284 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T77 | M77 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] |
