Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C000 / NLRP1_HUMAN
Protein Name NACHT, LRR and PYD domains-containing protein 1
Gene Name Name: NLRP1
Synonyms:CARD7,DEFCAP;
Organism Homo sapiens (Human)

PRO ID PR:Q9C000
DAG View
PRO Name NACHT, LRR and PYD domains-containing protein 1 (human)
Definition A NACHT, LRR and PYD domains-containing protein 1 that is encoded in the genome of human.
Short Label hNLRP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C000 (NLRP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T41 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
S823 Phosphorylation PhosphoSitePlus
K826 Ubiquitination PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
T1000 Phosphorylation PhosphoSitePlus
K1428 Acetylation PhosphoSitePlus
K1439 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T965 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K297 N297 Biomuta DOID:1612 / breast cancer [ tcga ]
T1000 K1000 Biomuta DOID:1324 / lung cancer [ cosmic ]