iPTMnet Report for Q9BZZ5 (API5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZZ5 / API5_HUMAN
Protein Name Apoptosis inhibitor 5
Gene Name Name: API5
ORFNames:MIG8;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZZ5
DAG View
PRO Name apoptosis inhibitor 5 (human)
Definition An apoptosis inhibitor 5 that is encoded in the genome of human.
Short Label hAPI5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZZ5 (API5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation PhosphoSitePlus
Y28 Phosphorylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K51 Acetylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K251 Acetylation PhosphoSitePlus   UniProt 22334682
K369 Ubiquitination PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus   UniProt 23186163
K448 Acetylation PhosphoSitePlus
K454 Acetylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
T460 Phosphorylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus
S462 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
S464 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 17081983, ...24275569, 20068231
S470 Phosphorylation PhosphoSitePlus
Y481 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
K487 Acetylation PhosphoSitePlus
K487 Methylation PhosphoSitePlus
R500 Methylation PhosphoSitePlus   UniProt 24129315
R504 Methylation PhosphoSitePlus
R507 Methylation PhosphoSitePlus
R510 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y28 Phosphorylation HPRD 19413330
T460 Phosphorylation HPRD 17081983, 20068231
T461 Phosphorylation HPRD 17081983
S462 Phosphorylation HPRD 19651622, 17081983, 20068231, ...19664995
S464 Phosphorylation HPRD 19413330, 19651622, 16083285, ...19664995, 20068231
S485 Phosphorylation PhosphoSitePlus
K487 Acetylation PhosphoSitePlus
K487 Methylation PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
Y497 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y28 C28 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K153 N153 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K169 E169 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc ]
K448 R448 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K454 Q454 Biomuta DOID:263 / kidney cancer [ cosmic ]